Project title: Transgenic Technology Laboratory
Contract term: Fixed term contract up to 15 months (maternity cover)
About us
The CRUK Scotland Institute is a cancer research institute, situated in Glasgow with approximately 250 researchers split across 30 research groups consisting of PIs, postdoctoral scientists, PhD students and scientific officers. It is one of Europe's leading cancer research centres, supporting cutting-edge work into the molecular mechanisms of cancer development. As well as core support from Cancer Research UK, the Institute also receives an additional third of its total income from external grants and industry collaborations. It has an excellent reputation for fundamental cancer research, including world-class metabolism studies and renowned in vivo modelling of tumour growth and metastasis. Its research ethos is about excellence, honesty, openness, accountability, and integrity.
Project outline
We currently have a position available for a Senior Scientific Officer in the Transgenic Technology laboratory. The primary role of this position will be to apply state-of the-art genome editing technology for the creation of genetically engineered in vivo cancer models.
You will be expected to work as part of a team applying CRISPR-Cas9, AAV gene delivery and targeted base editing approaches to directly generate new transgenic alleles, for discovery research. This will involve project design, routine molecular biology and data analysis, as well as preimplantation embryo handling and electroporation.
Ideally you should possess a PhD degree in molecular genetics or similar and previous experience in molecular biology is essential. You should be able to work both independently and in close collaboration with the scientists and technicians associated with the transgenic projects. You should be highly motivated and have good communication, project management and organisational skills. A flexible approach to your working pattern is necessary in this role.
Whilst previous experience of genome editing with targeted nucleases (e.g. CRISPR/Cas9) and embryo manipulation would be a significant advantage, we can provide the necessary training for candidates who can demonstrate excellent troubleshooting, planning/organisational capability, and have a relevant scientific background.
For informal enquiries please email Dr Douglas Strathdee:
d.strathdee@crukscotlandinstitute.ac.uk
Equality, Diversity and Inclusion
Our overarching research ethos at the Institute is about excellence, honesty, openness, accountability and integrity. The diversity of our staff and students is also what makes the Institute such a vibrant place to work and advance discoveries in cancer research. Family friendly policies, our collaborative ethos, a focus on good mental health and well-being and opportunities for all help to create an enjoyable and inclusive workplace where your voice matters.
Employee Benefits
Closing Date: 4th July 2025 but we may contact promising candidates on a rolling basis, so please apply as soon as you are ready.